The GunznGear channel reviews some options for home defense handguns, including both revolvers and semi-automatics.
Moss Pawn put together this video to help with selecting guns for the elderly. Guns Shown in Video: Walther P22 Glock 19 Smith & Wesson Bodyguard 38 North American Arms
A VIS 9mm Polish WWII Radom vs a mini NAA 22 revolver with a folding grip holster. (This is certainly an odd match up!) *NAA 22 Revolver Specs: 22 Long